Berge K E, Berg K
Institute of Medical Genetics, University of Oslo, Norway.
Clin Genet. 1994 Dec;46(6):433-5. doi: 10.1111/j.1399-0004.1994.tb04412.x.
We have examined healthy Norwegians with respect to two restriction fragment length polymorphisms at the locus for atrial natriuretic factor, detectable with the restriction enzymes XhoI and BglI, respectively. No association with systolic or diastolic blood pressure level or variability was found. Thus, the normal genes detected by examination of these restriction fragment length polymorphisms have neither "level gene" nor "variability gene" effects on normal blood pressure.
我们检测了健康挪威人在心房钠尿肽基因座上的两种限制性片段长度多态性,分别可用限制性内切酶XhoI和BglI检测到。未发现与收缩压或舒张压水平或变异性有关联。因此,通过检测这些限制性片段长度多态性所发现的正常基因对正常血压既没有“水平基因”效应,也没有“变异性基因”效应。