Berge K E, Berg K
Institute of Medical Genetics, University of Oslo, Norway.
Clin Genet. 1994 Dec;46(6):436-8. doi: 10.1111/j.1399-0004.1994.tb04413.x.
We have studied a normal restriction fragment length polymorphism at the renin locus, detected with the restriction enzyme BglI in healthy Norwegians. No association with blood pressure level or variability was found. Thus, the normal genes detected by examination of this restriction fragment length polymorphism at the renin locus have neither "level gene" nor "variability gene" effects on normal blood pressure.
我们研究了肾素基因座处的一种正常限制性片段长度多态性,该多态性是用限制性内切酶BglI在健康挪威人中检测到的。未发现其与血压水平或变异性有关联。因此,通过检测肾素基因座处的这种限制性片段长度多态性所发现的正常基因,对正常血压既没有“水平基因”效应,也没有“变异性基因”效应。