Dupre J N, Keenan M J, Hegsted M, Brudevold A M
School of Human Ecology, Louisiana State University Agricultural Center, Louisiana State University, Baton Rouge 70803.
Environ Health Perspect. 1994 Nov;102 Suppl 7(Suppl 7):55-8. doi: 10.1289/ehp.94102s755.
Although boron has long been known to be a required nutrient for plants, it was not until recently that there was any suggestion of a nutritional requirement for animals and humans. Addition of boron to the diet of vitamin D-deficient chicks indicated that boron may play a role in animal nutrition. Studies with rats have demonstrated that supplemental dietary boron has most marked effects when the diet is deficient in known nutrients. We observed higher apparent-balance values of calcium, magnesium, and phosphorus for rats fed a vitamin D-deprived diet with dietary supplemental boron (2.72 ppm), than for rats fed the same diet without added boron (0.16 ppm). The treatment group with dietary supplemental boron demonstrated a high degree of variability in response to boron. We hypothesize that relatively large and variable vitamin D stores in weanling rats from a colony supplemented with 3000 IU vitamin D/kg diet accounted for the observed variable response. A recent, unpublished study using weanling rats from a low-vitamin D colony appears to support this hypothesis.
虽然硼长期以来一直被认为是植物所需的营养元素，但直到最近才有关于动物和人类营养需求的迹象。在维生素D缺乏的雏鸡饮食中添加硼表明，硼可能在动物营养中发挥作用。对大鼠的研究表明，当饮食中缺乏已知营养素时，补充膳食硼的效果最为显著。我们观察到，喂食添加了膳食硼（2.72 ppm）的维生素D缺乏饮食的大鼠，其钙、镁和磷的表观平衡值高于喂食相同饮食但未添加硼（0.16 ppm）的大鼠。膳食补充硼的治疗组对硼的反应表现出高度的变异性。我们推测，来自补充了3000 IU维生素D/kg饮食的群体的断奶大鼠中相对大量且可变的维生素D储备，是观察到的可变反应的原因。最近一项未发表的研究，使用来自低维生素D群体的断奶大鼠，似乎支持了这一假设。
