• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

神经活动增加对大脑发育的影响。

Effects of increased neural activity on brain growth.

作者信息

Zheng D, Purves D

机构信息

Duke University Medical Center, Department of Neurobiology, Durham, NC 27710.

出版信息

Proc Natl Acad Sci U S A. 1995 Mar 14;92(6):1802-6. doi: 10.1073/pnas.92.6.1802.

DOI:10.1073/pnas.92.6.1802
PMID:7892181
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC42370/
Abstract

We have measured the effects of regionally increased metabolic activity--and by inference electrical activity--on cortical growth in the developing rat brain. Cortical growth is significantly and specifically greater in regions of chronically increased activity. This effect of activity on cortical growth may help explain the permanent storage of early experience in the developing nervous system.

摘要

我们已经测量了局部代谢活动增加——以及由此推断的电活动增加——对发育中大鼠大脑皮质生长的影响。在长期活动增加的区域,皮质生长显著且特异性地更大。活动对皮质生长的这种影响可能有助于解释早期经验在发育中的神经系统中的永久存储。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1234/42370/a40521866dec/pnas01484-0019-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1234/42370/a40521866dec/pnas01484-0019-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1234/42370/a40521866dec/pnas01484-0019-a.jpg

相似文献

1
Effects of increased neural activity on brain growth.神经活动增加对大脑发育的影响。
Proc Natl Acad Sci U S A. 1995 Mar 14;92(6):1802-6. doi: 10.1073/pnas.92.6.1802.
2
Barrelfield expansion after neonatal eye removal in mice.小鼠新生儿期眼球摘除术后的桶状区扩张
Neuroreport. 1992 Jun;3(6):489-92. doi: 10.1097/00001756-199206000-00008.
3
Glutamate receptor blockade at cortical synapses disrupts development of thalamocortical and columnar organization in somatosensory cortex.皮质突触处的谷氨酸受体阻断会破坏体感皮层中丘脑皮质和柱状组织的发育。
Proc Natl Acad Sci U S A. 1996 May 28;93(11):5584-9. doi: 10.1073/pnas.93.11.5584.
4
Functional connectivity of the sensorimotor area in naturally sleeping infants.自然睡眠婴儿感觉运动区的功能连接性
Brain Res. 2008 Aug 5;1223:42-9. doi: 10.1016/j.brainres.2008.05.054. Epub 2008 May 28.
5
Specializations of the human brain.人类大脑的特化
Sci Am. 1979 Sep;241(3):180-99. doi: 10.1038/scientificamerican0979-180.
6
Neonatal sensory deprivation and the development of cortical function: unilateral and bilateral sensory deprivation result in different functional outcomes.新生儿感觉剥夺与皮层功能发育:单侧和双侧感觉剥夺导致不同的功能结果。
J Neurophysiol. 2010 Jul;104(1):98-107. doi: 10.1152/jn.00120.2009. Epub 2010 Apr 28.
7
[Somatotopy and information processing in the somatosensory cortex].[躯体感觉皮层中的躯体定位与信息处理]
Brain Nerve. 2009 Dec;61(12):1373-82.
8
Direct cortical hemodynamic mapping of somatotopy of pig nostril sensation by functional near-infrared cortical imaging (fNCI).通过功能近红外皮层成像(fNCI)对猪鼻孔感觉的躯体定位进行直接皮层血流动力学映射。
Neuroimage. 2014 May 1;91:138-45. doi: 10.1016/j.neuroimage.2013.12.062. Epub 2014 Jan 11.
9
Functional brain imaging of young, nondemented, and demented older adults.年轻、未患痴呆症和患痴呆症的老年人的大脑功能成像。
J Cogn Neurosci. 2000;12 Suppl 2:24-34. doi: 10.1162/089892900564046.
10
Expression pattern of cadherins in the naked mole rat (Heterocephalus glaber) suggests innate cortical diversification of the cerebrum.钙黏蛋白在裸鼹鼠(Heterocephalus glaber)中的表达模式表明大脑皮质先天多样化。
J Comp Neurol. 2011 Jun 15;519(9):1736-47. doi: 10.1002/cne.22598.

引用本文的文献

1
Optimizing infant neuroimaging methods to understand the neurodevelopmental impacts of early nutrition and feeding.优化婴儿神经成像方法以了解早期营养和喂养对神经发育的影响。
Dev Cogn Neurosci. 2025 Jan;71:101481. doi: 10.1016/j.dcn.2024.101481. Epub 2024 Nov 23.
2
Bilateral enucleation at birth modifies calcium spike amplitude, but not frequency, in neurons of the somatosensory thalamus and cortex: Implications for developmental cross-modal plasticity.出生时双侧眼球摘除会改变体感丘脑和皮层神经元中钙峰的幅度,但不会改变其频率:对发育性跨模态可塑性的影响。
IBRO Rep. 2019 Nov 10;7:108-116. doi: 10.1016/j.ibror.2019.11.003. eCollection 2019 Dec.
3

本文引用的文献

1
Differential metabolic and electrical activity in the somatic sensory cortex of juvenile and adult rats.幼年和成年大鼠躯体感觉皮层的差异代谢和电活动
J Neurosci. 1993 Oct;13(10):4193-213. doi: 10.1523/JNEUROSCI.13-10-04193.1993.
2
Neonatal enucleation induces cross-modal changes in the barrel cortex of rat. A behavioural and electrophysiological study.新生大鼠眼球摘除术可诱导大鼠桶状皮质发生跨模态变化。一项行为学和电生理学研究。
Neurosci Lett. 1994 Feb 14;167(1-2):1-4. doi: 10.1016/0304-3940(94)91014-6.
3
Neural activity and the development of the somatic sensory system.
Neural Coding of Whisker-Mediated Touch in Primary Somatosensory Cortex Is Altered Following Early Blindness.
初级体感皮层中胡须介导的触摸的神经编码在早期失明后发生改变。
J Neurosci. 2018 Jul 4;38(27):6172-6189. doi: 10.1523/JNEUROSCI.0066-18.2018. Epub 2018 May 28.
4
Impact of thalamocortical input on barrel cortex development.丘脑皮质输入对桶状皮层发育的影响。
Neuroscience. 2018 Jan 1;368:246-255. doi: 10.1016/j.neuroscience.2017.04.005. Epub 2017 Apr 13.
5
Prenatal thalamic waves regulate cortical area size prior to sensory processing.产前丘脑波在感觉处理之前调节皮质区大小。
Nat Commun. 2017 Feb 3;8:14172. doi: 10.1038/ncomms14172.
6
A seed-based cross-modal comparison of brain connectivity measures.基于种子的脑连接性测量的跨模态比较。
Brain Struct Funct. 2017 Apr;222(3):1131-1151. doi: 10.1007/s00429-016-1264-3. Epub 2016 Jul 2.
7
Shifts in developmental timing, and not increased levels of experience-dependent neuronal activity, promote barrel expansion in the primary somatosensory cortex of rats enucleated at birth.出生时眼球摘除会促进大鼠初级体感皮层中桶状结构的扩张,而不是增加经验依赖性神经元活动的水平,这种扩张是由于发育时间的改变所致。
PLoS One. 2013;8(1):e54940. doi: 10.1371/journal.pone.0054940. Epub 2013 Jan 25.
8
Caudate asymmetry: a neurobiological marker of moderate prenatal alcohol exposure in young adults.尾状核不对称:青少年时期中度产前酒精暴露的神经生物学标志物。
Neurotoxicol Teratol. 2010 Nov-Dec;32(6):589-94. doi: 10.1016/j.ntt.2010.06.012. Epub 2010 Jul 6.
9
Late onset muscle plasticity in the whisker pad of enucleated rats.摘除眼球大鼠触须垫中的迟发性肌肉可塑性。
Proc Natl Acad Sci U S A. 2008 Oct 14;105(41):15973-8. doi: 10.1073/pnas.0808431105. Epub 2008 Oct 6.
10
Brain structures differ between musicians and non-musicians.音乐家和非音乐家的大脑结构有所不同。
J Neurosci. 2003 Oct 8;23(27):9240-5. doi: 10.1523/JNEUROSCI.23-27-09240.2003.
神经活动与躯体感觉系统的发育
Curr Opin Neurobiol. 1994 Feb;4(1):120-3. doi: 10.1016/0959-4388(94)90041-8.
4
Cerebral asymmetry and handedness.大脑不对称性与利手性。
Nature. 1994 Mar 17;368(6468):197-8. doi: 10.1038/368197a0.
5
Activity-dependent energy metabolism in rat posterior pituitary primarily reflects sodium pump activity.大鼠垂体后叶中依赖活动的能量代谢主要反映钠泵活性。
J Neurochem. 1980 Jan;34(1):213-5. doi: 10.1111/j.1471-4159.1980.tb04643.x.
6
Symposium summary. Neuronal activity and energy metabolism.
Fed Proc. 1981 Jul;40(9):2353-62.
7
Growth alteration in the auditory cortex of visually deprived mice.
J Comp Neurol. 1966 Mar;126(3):463-9. doi: 10.1002/cne.901260308.
8
The structural organization of layer IV in the somatosensory region (SI) of mouse cerebral cortex. The description of a cortical field composed of discrete cytoarchitectonic units.小鼠大脑皮层体感区(SI)IV层的结构组织。对由离散细胞构筑单位组成的皮质区域的描述。
Brain Res. 1970 Jan 20;17(2):205-42. doi: 10.1016/0006-8993(70)90079-x.
9
The organization and mutability of the forepaw and hindpaw representations in the somatosensory cortex of the neonatal rat.新生大鼠体感皮层中前爪和后爪表征的组织与可变性。
J Comp Neurol. 1987 Feb 8;256(2):246-56. doi: 10.1002/cne.902560205.
10
Histochemical demonstration of sensory maps in the rat and mouse cerebral cortex.大鼠和小鼠大脑皮质感觉图谱的组织化学显示
Brain Res. 1987 Aug 18;418(1):178-82. doi: 10.1016/0006-8993(87)90977-2.