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神经活动与躯体感觉系统的发育

Neural activity and the development of the somatic sensory system.

作者信息

Purves D, Riddle D R, White L E, Gutierrez-Ospina G

机构信息

Department of Neurobiology, Duke University Medical Center, Durham, North Carolina 27710.

出版信息

Curr Opin Neurobiol. 1994 Feb;4(1):120-3. doi: 10.1016/0959-4388(94)90041-8.

DOI:10.1016/0959-4388(94)90041-8
PMID:8173318
Abstract

Present thinking about the role of neural activity in the developing brain is based largely upon observations in the visual system. Attempts to generalize these findings in the somatic sensory system, however, have yielded perplexing results. Unlike the visual system, recent evidence suggests that activity plays a relatively minor role in establishing structural patterns in the primary somatic sensory cortex. Activity levels in the primary somatic sensory cortex are nonetheless highest in those regions that grow most during postnatal development, implying that activity promotes differential cortical growth.

摘要

目前对于神经活动在发育中大脑的作用的认识,很大程度上基于视觉系统的观察结果。然而,试图将这些发现在躯体感觉系统中进行推广时,却得出了令人困惑的结果。与视觉系统不同,最近的证据表明,活动在初级躯体感觉皮层建立结构模式方面所起的作用相对较小。尽管如此,初级躯体感觉皮层中活动水平在出生后发育期间生长最多的那些区域是最高的,这意味着活动促进了皮层的差异性生长。

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