Sandermann H
Institut für Biochemische Pflanzenpathologie, GSF-Forschungszentrum für Umwelt und Gesundheit GmbH, Oberschleissheim, FRG.
Pharmacogenetics. 1994 Oct;4(5):225-41. doi: 10.1097/00008571-199410000-00001.
Xenobiotic metabolism in plants resembles that in animal liver on the levels of metabolite patterns, enzyme classes and cDNA sequences. Historical and current evidence for the 'green liver' concept of xenobiotic plant metabolism is presented. Xenobiotic residues resulting from phase I (transformation) and phase II (conjugation) are usually stored in the plant tissue in phase III (compartmentation). The following topics are discussed: residue toxicology, metabolic modelling, enzyme inducibility and enzyme evolution.
植物中的异生物质代谢在代谢物模式、酶类和cDNA序列水平上与动物肝脏中的相似。本文介绍了异生物质植物代谢的“绿色肝脏”概念的历史和当前证据。由I相（转化）和II相（结合）产生的异生物质残留物通常在III相（区室化）中储存于植物组织中。讨论了以下主题：残留物毒理学、代谢建模、酶诱导性和酶进化。
