Watanabe N, Seto H, Sato S, Simizu M, Wu Y W, Kageyama M, Nomura K, Kakishita M
Department of Radiology, Toyama Medical and Pharmaceutical University, Japan.
Clin Nucl Med. 1995 Jan;20(1):61-4. doi: 10.1097/00003072-199501000-00015.
A patient with neuro-Behcet disease is described. SPECT using Tc-99m HMPAO was performed to evaluate brain perfusion. The brain SPECT revealed decreased perfusion in the right frontal, parietal, temporal, and occipital lobes. MRI showed high intensity lesions in the white matter in the right periventricular centrum semiovale and frontal region on T2 weighted images. Gray matter abnormalities were evident on brain SPECT, but not on MRI. Brain SPECT using Tc-99m HMPAO may provide useful clinical information on regional cerebral cortical abnormalities associated with neuro-Behcet disease.
本文描述了一名患有神经白塞病的患者。使用锝-99m六甲基丙烯胺肟（Tc-99m HMPAO）进行单光子发射计算机断层扫描（SPECT）以评估脑灌注。脑SPECT显示右侧额叶、顶叶、颞叶和枕叶灌注减少。磁共振成像（MRI）在T2加权图像上显示右侧脑室周围半卵圆中心和额叶区域的白质有高强度病变。脑SPECT上灰质异常明显，但MRI上不明显。使用Tc-99m HMPAO的脑SPECT可能为与神经白塞病相关的局部大脑皮质异常提供有用的临床信息。
