[A new type of locus-specific instability in Drosophila melanogaster not dependent on P-M hybrid dysgenesis].

In analysis of instability at loci yellow and scute, induced by introduction of the active P-element transposase into the genome of line y2nsscme, alleles of these loci with transposase-independent instability were selected. The mutation rate of these alleles reached tens of percent. Two types of transposase-independent instability were described: (1) instability limited to the scute locus and (2) instability at both yellow and scute loci.