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[黑腹果蝇黄色基因座中超不稳定突变的特性]

[Properties of super unstable mutations in the Drosophila melanogaster yellow locus].

作者信息

Georgiev P G, Elagin V A, Buff E M, Koliagin N P

出版信息

Genetika. 1992 Apr;28(4):98-107.

PMID:1639253
Abstract

The properties of super-unstable systems of the white, singed and ocetilless loci obtained as a result of P-M dysgenesis induction in the strains with a mobilized Stalker were described earlier. In the studies of super-instability in ocetilless locus, six super-unstable mutations in the yellow locus were obtained. Detailed genetic analysis was performed resulting in isolation of 80 alleles with different phenotype expression. In general, super-instability in the yellow locus reminds that in the white and ocetilless loci. Most of alleles are highly unstable possessing a characteristic pattern of mutation changes. Also, sub-systems were found in the yellow super-unstable system. Each consists of several mutually inter-converting alleles which possess a characteristic phenotype, mode and rate of mutation changes.

摘要

先前已描述了在具有可移动追踪元件的品系中,由于P-M杂种不育诱导而获得的白色、焦刚毛和无刚毛位点的超不稳定系统的特性。在对无刚毛位点超不稳定性的研究中,在黄色位点获得了六个超不稳定突变。进行了详细的遗传分析,分离出80个具有不同表型表达的等位基因。总体而言,黄色位点的超不稳定性与白色和无刚毛位点的情况相似。大多数等位基因高度不稳定,具有特征性的突变变化模式。此外,在黄色超不稳定系统中发现了子系统。每个子系统由几个相互转化的等位基因组成,这些等位基因具有特征性的表型、突变变化模式和速率。

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