Okada K, Sakata H, Shirane M, Minamoto A, Choshi K
Department of Ophthalmology, Hiroshima University School of Medicine, Japan.
Hiroshima J Med Sci. 1994 Sep;43(3):111-3.
Morning glory syndrome (MGS), an uncommon optic disc anomaly, is characterized by a funnel-shaped, excavated optic disc surrounded by chorioretinal pigmentary disturbance. Generally, it is an isolated ocular abnormality. The authors describe two patients in whom MGS developed in association with brain abnormalities. In both cases, there was enlargement of the optic nerve that showed increased radiodensity similar to that of sclera and cavum vergae in the brain cavity present in computerized tomography (CT). To our knowledge, the coexistence of MGS, cavum vergae and an enlarged retrobulbar optic nerve showing increased radiodensity have not been previously reported. The findings suggest that MGS may be based on a developmental anomaly involving the brain, and the enlarged optic nerve may be associated with sclera because of the isodensity in CT.
牵牛花综合征（MGS）是一种罕见的视盘异常，其特征为呈漏斗状、凹陷的视盘，周围伴有脉络膜视网膜色素紊乱。通常，它是一种孤立的眼部异常。作者描述了两名牵牛花综合征与脑部异常相关的患者。在这两个病例中，视神经均增粗，在计算机断层扫描（CT）中显示出与巩膜相似的放射性密度增加，并且脑腔内有透明隔腔。据我们所知，此前尚未报道过牵牛花综合征、透明隔腔以及球后视神经增粗且放射性密度增加同时存在的情况。这些发现表明，牵牛花综合征可能基于涉及脑部的发育异常，并且由于CT中的等密度，增粗的视神经可能与巩膜有关。
