Katz V L, Lim W
Department of Ob/Gyn, UNC Hospital, Chapel Hill.
N C Med J. 1995 Feb;56(2):102-4.
It appears that pregnancy itself is not adversely affected by HIV infection, but the course of HIV infection in the mother may be accelerated by pregnancy. The results of the 076 trial have changed our approach to AIDS in pregnancy. Heretofore AZT was only given for maternal indications such as severe immunodeficiency (CD4 count less than 200). We now recommend that AZT be given to all women with HIV infection and to infants postpartum. As to mode of delivery, Cesarean section may be beneficial, but we await further studies. We strongly encourage all pregnant women to have HIV testing regardless of risk factors. The HIV epidemic is here, in North Carolina. It is our responsibility as doctors to help pregnant women as best we can with their disease.
看来怀孕本身不会受到艾滋病毒感染的不利影响，但怀孕可能会加速母亲体内艾滋病毒感染的进程。076试验的结果改变了我们对孕期艾滋病的治疗方法。在此之前，齐多夫定（AZT）仅用于治疗诸如严重免疫缺陷（CD4细胞计数低于200）等母体指征。我们现在建议对所有感染艾滋病毒的妇女及其产后婴儿都使用AZT。至于分娩方式，剖宫产可能有益，但我们还在等待进一步的研究结果。我们强烈鼓励所有孕妇进行艾滋病毒检测，无论其是否有风险因素。北卡罗来纳州已经出现了艾滋病毒流行疫情。作为医生，我们有责任尽最大努力帮助感染此病的孕妇。
