Picard E, Gillis D, Klapholz L, Schreiber L, Engelhard D
Department of Pediatrics, Hadassah University, Ein-Kerem, Jerusalem, Israel.
Pediatr Dermatol. 1994 Dec;11(4):331-4. doi: 10.1111/j.1525-1470.1994.tb00099.x.
Toxic epidermal necrolysis (TEN) is a rare condition in childhood usually attributed to drugs. We describe a 4-month-old infant who developed typical clinical and histologic findings of TEN concomitantly with Klebsiella pneumoniae sepsis. We emphasize that in cases of acute, severe exfoliative disease in infants, apart from staphylococcal infection, gram-negative bacterial sepsis must also be considered.
中毒性表皮坏死松解症(TEN)在儿童期较为罕见,通常由药物引起。我们描述了一名4个月大的婴儿,其出现了典型的TEN临床和组织学表现,同时伴有肺炎克雷伯菌败血症。我们强调,对于婴儿急性、严重的剥脱性疾病,除了葡萄球菌感染外,还必须考虑革兰氏阴性菌败血症。