Calderón-Jaimes E, Conde-González C, Juárez Figueroa L, Uribe-Zúñiga P, Uribe-Salas F, Olamendi-Portugal M, Hernández-Avila M
Instituto Nacional de Salud Pública (INSP), Cuernavaca, Mor.
Rev Invest Clin. 1994 Nov-Dec;46(6):431-6.
This paper describes a serological survey applied to 3098 female commercial sex workers, in order to determine the prevalence of syphilis. The women attend regularly an AIDS orientation center sponsored by CONASIDA in Mexico City. The laboratory tests included the rapid plasma reagin assay (presumptive analysis) and the fluorescent treponemal antibody-absorption technique (confirmatory test). No primary syphilis cases were detected and the prevalence of latent asymptomatic syphilis was 8.2% (255/3098). The sensitivity and specificity of the presumptive test compared to the confirmatory test were 74% and 98% respectively, and the positive predictive value was 77% and the negative predictive value 98%. All seropositive women received the standard penicillin treatment for syphilis. Considerations of importance are offered regarding interpretation and usefulness of this kind of research.
本文描述了一项针对3098名女性商业性工作者进行的血清学调查，以确定梅毒的患病率。这些女性定期前往墨西哥城由国家艾滋病防治委员会（CONASIDA）赞助的艾滋病宣传中心。实验室检测包括快速血浆反应素试验（初步分析）和荧光密螺旋体抗体吸收技术（确证试验）。未检测到一期梅毒病例，潜伏无症状梅毒的患病率为8.2%（255/3098）。与确证试验相比，初步试验的敏感性和特异性分别为74%和98%，阳性预测值为77%，阴性预测值为98%。所有血清学阳性的女性均接受了梅毒的标准青霉素治疗。文中还就这类研究的解释和实用性提出了重要的注意事项。
