绵羊后外侧脊柱融合术的实验模型。第1部分。自体骨移植的实验步骤及结果
Experimental model of posterolateral spinal arthrodesis in sheep. Part 1. Experimental procedures and results with autologous bone graft.
作者信息
Guigui P, Plais P Y, Flautre B, Viguier E, Blary M C, Sales De Gauzy J, Chopin D, Lavaste F, Hardouin P
机构信息
Institut de Recherche sur les Maladies du Squelette, Berck sur Mer, France.
出版信息
Spine (Phila Pa 1976). 1994 Dec 15;19(24):2791-7. doi: 10.1097/00007632-199412150-00011.
OBJECTIVES
The authors evaluated the reliability in obtaining a posterolateral spinal arthrodesis (PSA) with autologous bone graft.
SUMMARY OF BACKGROUND DATA
Posterolateral spinal arthrodesis using autogenous cancellous bone graft is the most simple and efficient technique to get a spinal graft. No extensive biomechanical study of PSA is available. Thus, an experimental model of PSA is needed.
METHODS
Eleven sheep underwent lumbar autologous bone grafts and Cotrel-Dubousset instrumentations, and four sheep were used as controls. Sacrifice and biomechanical evaluation of the lumbar spines were performed after 1 year.
RESULTS
All grafts appeared continuous. A large decrease of flexibility (in rotation and in translation) was found in grafted spines in every direction. Failure in extension occurred at a mean value of 35.26 +/- 3.71 Nm.
CONCLUSION
A constant and homogenous PSA appears to be obtained in sheep under conditions close to the human surgery.
目的
作者评估了使用自体骨移植获得后外侧脊柱融合术（PSA）的可靠性。
背景资料总结
使用自体松质骨移植进行后外侧脊柱融合术是获得脊柱移植的最简单、有效的技术。目前尚无关于PSA的广泛生物力学研究。因此，需要一个PSA的实验模型。
方法
11只绵羊接受了腰椎自体骨移植和Cotrel-Dubousset器械固定，4只绵羊作为对照。1年后对腰椎进行处死和生物力学评估。
结果
所有移植骨均呈现连续性。在各个方向上，移植脊柱的柔韧性（旋转和移位方面）均大幅下降。伸展失败时的平均值为35.26 +/- 3.71 Nm。
结论
在接近人类手术的条件下，绵羊似乎能获得持续且均匀的PSA。
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