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马尔堡外科研究实验:临床外科医生与理论外科医生合作的五年经验

Marburg experiment on surgical research: a five-years' experience on the cooperation between clinical and theoretical surgeons.

作者信息

Lorenz W, Hamelmann H, Troidl H

出版信息

Klin Wochenschr. 1976 Oct 1;54(19):927-36. doi: 10.1007/BF01469006.

DOI:10.1007/BF01469006
PMID:790010
Abstract

The organisation of surgical research in Marburg is an experiment which has run for five-years and war carried out in attempt to establish a cooperation between clinical and theoretical surgeons (scientists in basic research). The experiment was started 1970 by creating a Division of Experimental Surgery and Pathological Biochemistry at the Surgery Clinic of the University. Structures and functions in this experiment were 6 small working teams, special services for the teams and for the whole Department of Surgery as well as a training programme in surgical research for theoretical surgeons. Success and failure in the experiment were evaluated by criteria testing three principal functions of surgical research: Training of clinical and theoretical surgeons in methods and techniques of surgical research, performance of controlled clinical trials and basic research in surgery. The early results of the Marburg experiment seem to be promising.

摘要

马尔堡外科研究的组织是一项已经进行了五年的试验,旨在尝试建立临床外科医生和理论外科医生(基础研究科学家)之间的合作。该试验始于1970年,当时在大学外科诊所设立了实验外科和病理生物化学分部。该试验中的架构和职能包括6个小型工作团队、为这些团队以及整个外科系提供的特殊服务,以及为理论外科医生开展的外科研究培训项目。通过检验外科研究三项主要职能的标准来评估该试验的成败:对临床和理论外科医生进行外科研究方法和技术培训、开展对照临床试验以及进行外科基础研究。马尔堡试验的早期结果似乎很有前景。

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引用本文的文献

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Histamine and stress ulcer: new components in organizing a sequential trial on cimetidine prophylaxis in seriously ill patients and definition of a special group at risk (severe polytrauma).组胺与应激性溃疡:关于西咪替丁预防重症患者应激性溃疡序贯试验的新要素及特殊高危组(严重多发伤)的定义
Klin Wochenschr. 1980 Jul 1;58(13):653-65. doi: 10.1007/BF01478603.
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Histamine and peptic ulcer: influence of sample-taking on the precision and accuracy of fluorometric histamine assay in biopsies of human gastric mucosa.组胺与消化性溃疡:取样对人胃黏膜活检中荧光法组胺测定的精密度和准确性的影响。
Agents Actions. 1980 Apr;10(1 Pt 2):175-85. doi: 10.1007/BF02024207.
3

本文引用的文献

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The billroth-I and Polya operations for duodenal ulcer; a comparison.十二指肠溃疡的毕罗一式和波利亚手术:一项比较。
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Theoretical surgery: a new specialty in operative medicine.
理论外科学:手术医学中的一个新专业。
World J Surg. 1989 May-Jun;13(3):292-9. doi: 10.1007/BF01659037.
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Histamine and peptic ulcer: a prospective study of mucosal histamine concentration in duodenal ulcer patients and in control subjects suffering from various gastrointestinal diseases.组胺与消化性溃疡:十二指肠溃疡患者及患有各种胃肠道疾病的对照受试者黏膜组胺浓度的前瞻性研究。
Klin Wochenschr. 1976 Oct 1;54(19):947-56. doi: 10.1007/BF01469008.
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[Management of a systematic follow-up clinic (author's transl)].
Langenbecks Arch Chir. 1978 Nov;347:467-80. doi: 10.1007/BF01579377.
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标准化手术的前瞻性对照试验:治疗慢性十二指肠溃疡的选择性迷走神经切断术的选择与手术技术(作者译)
Klin Wochenschr. 1973 May 15;51(10):47-86. doi: 10.1007/BF01467825.
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[Interdisciplinary co-operation in surgery].[外科领域的跨学科合作]
Ther Umsch. 1972 Nov;29(11):645-51.
7
[International cooperation in clinical research. Illustrated on the example of the International Task Force for Problems in Osteosynthesis].[临床研究中的国际合作。以骨接合术问题国际特别工作组为例进行说明]
Chirurg. 1974 Nov;45(11):494-9.
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[Task and organization of clinico-surgical research].[临床外科研究的任务与组织]
Chirurg. 1974 Nov;45(11):490-4.
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[The dilemma of surgical research].[外科研究的困境]
Chirurg. 1974 Nov;45(11):485-90.
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Evaluation of histamine elimination curves in plasma and whole blood of several circulatory regions: a method for studying kinetics of histamine release in the whole animal.几个循环区域血浆和全血中组胺消除曲线的评估:一种研究全动物体内组胺释放动力学的方法。
Agents Actions. 1974 Dec;4(5):336-56. doi: 10.1007/BF01964936.