Khazizov I E
Lik Sprava. 1994 Jul-Aug(7-8):64-70.
Characteristics of haemogramme were studied in 28 patients with eczema, 25 patients with neurodermatitis disseminata, 38 patients with cutaneous form of psoriasis, in whom dermatosis was manifested by extensive skin involvement. Statistical data on relative and absolute values for the groups studied confirm the rise in the numbers of monocytes, eosinophiles, lymphocytes and segmentonuclear neutrophils in the peripheral blood, this being most characteristic abnormality in the haemogramme, which was particularly noticeable in patients with clinically apparent acuity of cutaneous manifestations, universal or erythrodermic type of its affliction, lingering exacerbation state. Current knowledge about hemopoiesis and pathogenesis of the above dermatoses allow the changes being detected in the haemogramme to be considered secondary to chronic unspecific inflammation developing in the skin, being characterized, from the immunological standpoint, in a general sense, by T-cellular (tissue) immunodeficiency.
对28例湿疹患者、25例播散性神经性皮炎患者、38例皮肤型银屑病患者的血常规特征进行了研究，这些患者的皮肤病表现为广泛的皮肤受累。所研究组的相对和绝对值统计数据证实，外周血中单核细胞、嗜酸性粒细胞、淋巴细胞和分叶核中性粒细胞数量增加，这是血常规中最典型的异常，在皮肤表现具有临床明显急性发作、普遍或红皮病型受累、持续加重状态的患者中尤为明显。目前关于上述皮肤病的造血和发病机制的知识使得在血常规中检测到的变化被认为是皮肤中发生的慢性非特异性炎症的继发表现，从免疫学角度来看，总体上其特征为T细胞（组织）免疫缺陷。
