Stepniak-Ziółkiewicz I
Ze Szpitala Chorób Płuc w Orzeszu.
Wiad Lek. 1993 Dec;46(23-24):919-21.
The presented literature on the function of hypothalamo-hypophyseal-thyroid axis in patients with pulmonary malignancies is unequivocal. No clinical manifestations of thyroid dysfunction were observed, however, laboratory investigations have demonstrated significant impairment of the axis function. Most frequently a decrease of T3 concentration with normal TSH level occurred in the serum of patients. Attempts at explanation of the disturbances in hypothalamo-hypophyseal-thyroid axis function are still at hypothesis stage.
关于下丘脑 - 垂体 - 甲状腺轴在肺部恶性肿瘤患者中的功能,现有文献观点明确。然而,尽管未观察到甲状腺功能障碍的临床表现,但实验室检查已证实该轴功能存在显著损害。患者血清中最常见的情况是T3浓度降低而TSH水平正常。对下丘脑 - 垂体 - 甲状腺轴功能紊乱的解释仍处于假说阶段。