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β-肾上腺素能受体阻断药氧烯洛尔治疗焦虑症的对照评估

Controlled evaluation of the beta adrenoceptor blocking drug oxprenolol in anxiety.

作者信息

Johnson G, Singh B, Leeman M

出版信息

Med J Aust. 1976 Jun 12;1(24):909-12.

PMID:790112
Abstract

An investigation of the effectiveness of the beta adrenoceptor blocking drug oxprenolol in the treatment of primary clinical anxiety is reported. A controlled double-blind evaluation of oxprenolol versus diazepam and placebo was carried out. The results of the trial showed diazepam to be generally more effective and to produce a more rapid onset of symptom reduction than oxprenolol. The role of beta adrenergic blocking drugs in the treatment of clinical anxiety and related syndromes is discussed.

摘要

本文报道了对β肾上腺素能受体阻滞剂氧烯洛尔治疗原发性临床焦虑症有效性的一项研究。对氧烯洛尔与地西泮及安慰剂进行了对照双盲评估。试验结果表明,地西泮总体上比氧烯洛尔更有效,且症状减轻起效更快。文中讨论了β肾上腺素能阻断药物在治疗临床焦虑症及相关综合征中的作用。

相似文献

1
Controlled evaluation of the beta adrenoceptor blocking drug oxprenolol in anxiety.β-肾上腺素能受体阻断药氧烯洛尔治疗焦虑症的对照评估
Med J Aust. 1976 Jun 12;1(24):909-12.
2
[A double blind trial : oxprenolol/diazepam (author's transl)].[双盲试验:氧烯洛尔/地西泮(作者译)]
Encephale. 1981;7(1):51-8.
3
Diazepam and phenobarbital in the treatment of anxiety: a controlled multicenter study using physician and patient rating scales.
Curr Ther Res Clin Exp. 1976 Aug;20(2):184-93.
4
A placebo controlled trial of diazepam and oxprenolol for anxiety.一项关于地西泮和氧烯洛尔治疗焦虑症的安慰剂对照试验。
Psychopharmacology (Berl). 1976 Nov 10;50(2):177-9. doi: 10.1007/BF00430489.
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Bromazepam and diazepam in generalized anxiety: a placebo-controlled study with measurement of drug plasma concentrations.溴西泮和地西泮治疗广泛性焦虑症:一项测量药物血浆浓度的安慰剂对照研究。
J Clin Psychopharmacol. 1983 Apr;3(2):80-7.
6
Oxprenolol and propranolol in anxiety states. A double-blind comparative study.
S Afr Med J. 1976 Apr 10;50(16):627-9.
7
Beta-adrenergic blocking drugs in anxiety and stress.β-肾上腺素能阻断药物在焦虑和应激中的作用
Psychiatr Clin North Am. 1985 Mar;8(1):119-32.
8
Comparative evaluation of benzoctamine and diazepam in treatment of anxiety.
J Clin Pharmacol J New Drugs. 1970 May-Jun;10(3):194-8.
9
Effect of alprazolam and diazepam on anxiety and panic attacks in panic disorder: a controlled study.阿普唑仑和地西泮对惊恐障碍中焦虑和惊恐发作的影响:一项对照研究。
J Clin Psychiatry. 1986 Sep;47(9):458-60.
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Oxprenolol in myocardial infarction survivors: brief review of the European Infarction Study results in the light of other beta-blocker post infarction trials.心得平用于心肌梗死幸存者:结合其他β受体阻滞剂心肌梗死后试验对欧洲梗死研究结果的简要综述。
Z Kardiol. 1985;74 Suppl 6:165-72.

引用本文的文献

1
Current status of beta-blocking drugs in the treatment of anxiety disorders.
Drugs. 1988 Dec;36(6):773-83. doi: 10.2165/00003495-198836060-00006.
2
Anxiolytic effects of acebutolol and atenolol in healthy volunteers with induced anxiety.醋丁洛尔和阿替洛尔对诱发焦虑的健康志愿者的抗焦虑作用。
Psychopharmacology (Berl). 1988;95(2):245-9. doi: 10.1007/BF00174517.
3
A placebo controlled trial of diazepam and oxprenolol for anxiety.一项关于地西泮和氧烯洛尔治疗焦虑症的安慰剂对照试验。
Psychopharmacology (Berl). 1976 Nov 10;50(2):177-9. doi: 10.1007/BF00430489.