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秀丽隐杆线虫同源异型框基因簇。

The Caenorhabditis elegans homeobox gene cluster.

作者信息

Bürglin T R, Ruvkun G

机构信息

Department of Molecular Biology, Harvard Medical School, Massachusetts General Hospital, Boston 02114.

出版信息

Curr Opin Genet Dev. 1993 Aug;3(4):615-20. doi: 10.1016/0959-437x(93)90097-9.

Abstract

Understanding of the C. elegans homeobox gene cluster has been significantly expanded since the genes egl-5 and lin-39 have been shown to correspond to homeobox genes in the cluster. Genes of the homeobox cluster not only function as regionally restricted homeotic genes along the anterior-posterior body axis, but also control cell migrations within the affected body regions.

摘要

自从已证明egl-5和lin-39基因与该基因簇中的同源框基因相对应以来,对秀丽隐杆线虫同源框基因簇的了解已显著扩展。同源框基因簇中的基因不仅作为沿前后体轴区域受限的同源异型基因发挥作用,而且还控制受影响身体区域内的细胞迁移。

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