Vincent-Houdek M, Muytjens H L, Bongaerts G P, van Ketel R J
Department of Infection Prevention, University Hospital Nijmegen, The Netherlands.
J Hosp Infect. 1993 Oct;25(2):117-24. doi: 10.1016/0195-6701(93)90102-6.
Of 21 cases of legionellosis, 14 were of nosocomial origin and 6 others had a possible nosocomial source. The hot and cold water systems, respiratory therapy equipment, puddles of rain water on flat roofs and in gutters, and demineralized water systems were all excluded as a source of nosocomial infection. By subtyping it was shown that Legionella pneumophila serogroup 1 isolates from 11 patients and from the cooling towers were indistinguishable. Because of this result the cooling towers were considered to be the infection source. After effective chlorination of the cooling towers, the frequency of legionellosis declined.
在21例军团病病例中，14例为医院感染源，另有6例可能源于医院。医院感染源排除了冷热水系统、呼吸治疗设备、平屋顶和排水沟中的雨水坑以及软化水系统。通过分型显示，从11名患者和冷却塔分离出的嗜肺军团菌血清1型菌株无法区分。基于这一结果，冷却塔被认为是感染源。对冷却塔进行有效氯化处理后，军团病的发病率下降。
