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急性心肌梗死:男性与女性在治疗方面的差异。

Acute myocardial infarction: difference in the treatment between men and women.

作者信息

Dellborg M, Swedberg K

机构信息

Department of Medicine, Ostra Hospital, University of Göteborg, Sweden.

出版信息

Qual Assur Health Care. 1993 Sep;5(3):261-5. doi: 10.1093/intqhc/5.3.261.

Abstract

During the last decade, treatment of myocardial infarction has changed and the prognosis dramatically improved. A sex bias in considering revascularization in men and women with coronary heart disease has been reported. The influence of gender on treatment given to patients with an acute myocardial infarction has not been investigated. From 1989 to 1991 there were 1515 patients with acute myocardial infarction admitted to the coronary care unit at Ostra Hospital; 67% were men. Pharmacological treatment limiting infarct size was given to 60% of all women and to 67% of all men; p < 0.05. In addition, coronary angiography during the hospital stay was performed in 0.2% of all women vs 1.9% of all men; p < 0.05. The prevalence of diabetes, age, symptoms or prehospital delay cannot explain these findings. While a sex bias in referring patients for revascularization has been reported, this report also describes a possible sex bias in the pharmacological treatment of acute myocardial infarction.

摘要

在过去十年间,心肌梗死的治疗方法发生了变化,预后也显著改善。据报道,在考虑对冠心病男性和女性进行血运重建时存在性别偏见。然而,性别对急性心肌梗死患者治疗的影响尚未得到研究。1989年至1991年期间,奥斯特拉医院冠心病监护病房收治了1515例急性心肌梗死患者,其中67%为男性。所有女性中有60%接受了限制梗死面积的药物治疗,所有男性中有67%接受了该治疗,p<0.05。此外,住院期间进行冠状动脉造影的女性占所有女性的0.2%,男性占所有男性的1.9%,p<0.05。糖尿病患病率、年龄、症状或院前延误均无法解释这些结果。虽然已有报道称在推荐患者进行血运重建时存在性别偏见,但本报告还描述了急性心肌梗死药物治疗中可能存在的性别偏见。

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