Kohli-Kumar M, Shahidi N T, Broxmeyer H E, Masterson M, Delaat C, Sambrano J, Morris C, Auerbach A D, Harris R E
Division of Pediatric Hematology/Oncology, Children's Hospital Medical Center, Cincinnati, Ohio 45229-2899.
Br J Haematol. 1993 Oct;85(2):419-22. doi: 10.1111/j.1365-2141.1993.tb03192.x.
There have only been a few reports documenting the use of umbilical cord blood as a source of stem cells for haemopoietic reconstitution. We report our experience with a child with Fanconi anaemia (FA) who underwent a stem cell transplant using umbilical cord blood cells from his HLA matched sibling. Although the engraftment was somewhat slow, it was complete and comparable to other transplants performed in FA patients using HLA matched sibling marrow. There was no graft-versus-host disease. The post-transplant period was uncomplicated and, at a follow-up of 36 months, this child is well with normal blood counts and immune function.
仅有少数报告记录了使用脐带血作为造血重建干细胞来源的情况。我们报告了一名范可尼贫血（FA）患儿的治疗经历，该患儿接受了来自其 HLA 匹配同胞的脐带血细胞进行的干细胞移植。尽管植入过程有些缓慢，但最终完全成功，且与使用 HLA 匹配同胞骨髓对 FA 患者进行的其他移植效果相当。未发生移植物抗宿主病。移植后过程顺利，在 36 个月的随访中，该患儿情况良好，血常规和免疫功能正常。
