Nikolic J, Péclard N, Deléamont P, Chavaz P, Schifferli J, Bounameaux H
Department of Medicine, University Hospital of Geneva, Switzerland.
Vasa. 1993;22(4):347-51.
A diagnosis of aortic insufficiency and mitral stenosis was made in a 24-year-old woman after an episode of heart failure following delivery. A double valvular replacement was performed 4 years later. At that time she suffered from recurrent episodes of erythema nodosum like lesions with an histological diagnosis of cutaneous polyarteritis nodosa. After another 4-year interval she presented with severe arterial hypertension and a biological inflammatory syndrome. An arteriography disclosed stenoses of the abdominal aorta, renal, and iliac arteries as well as occlusion of the right subclavian artery, diagnostic of Takayasu arteritis. We postulate that this woman presented a rare combination of cardiac and skin involvement of Takayasu's disease which preceded the classical arteritis of the aortic branches by 8 and 4 years, respectively.
一名24岁女性在产后发生心力衰竭后被诊断为主动脉瓣关闭不全和二尖瓣狭窄。4年后进行了双瓣膜置换术。当时她反复出现结节性红斑样病变，组织学诊断为皮肤结节性多动脉炎。又过了4年，她出现了严重的动脉高血压和生物性炎症综合征。血管造影显示腹主动脉、肾动脉和髂动脉狭窄以及右锁骨下动脉闭塞，诊断为大动脉炎。我们推测，这名女性出现了大动脉炎罕见的心脏和皮肤受累组合，分别比主动脉分支的典型动脉炎早8年和4年。
