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鸡不同年龄阶段L-亮氨酸的肠道转运:抗球虫药的影响

L-leucine intestinal transport at different ages in chicken: effect of anticoccidial drugs.

作者信息

Gonzalez G, Vinardell M P

机构信息

Departament de Ciencies Fisiologiques Humanes i de la Nutrició, Facultat de Farmàcia, Barcelona, Spain.

出版信息

Comp Biochem Physiol Comp Physiol. 1993 Dec;106(4):809-11. doi: 10.1016/0300-9629(93)90401-o.

DOI:10.1016/0300-9629(93)90401-o
PMID:7906640
Abstract
  1. L-Leucine transport by everted slices of duodenum, jejunum ileum and cecum of 1-, 2- and 3-week-old chickens has been determined. 2. The effects of the administration with the diet of three anticoccidial drugs: monensin, maduromicin ammonium and nicarbazine have been studied. 3. In the control animals, there is a reduction on intestinal transport with age, except in the duodenum which is not age-dependent. 4. Momensine induces an increase on leucine transport in the duodenum and cecum at all ages studied and only in the 3-week-old animals in the jejunum and ileum. 5. Nicarbazine reduces jejunal absorption of leucine and does not affect the function of the other segments. 6. Maduromicin ammonium has almost no effect on the absorptive process.
摘要
  1. 已测定1周龄、2周龄和3周龄雏鸡十二指肠、空肠、回肠和盲肠外翻肠段对L-亮氨酸的转运。2. 研究了在日粮中添加三种抗球虫药:莫能菌素、马杜霉素铵和尼卡巴嗪的效果。3. 在对照动物中,肠道转运随年龄增长而降低,但十二指肠除外,十二指肠的转运不依赖年龄。4. 在所研究的所有年龄段,莫能菌素均可使十二指肠和盲肠的亮氨酸转运增加,而仅在3周龄动物的空肠和回肠中增加。5. 尼卡巴嗪可降低空肠对亮氨酸的吸收,且不影响其他肠段的功能。6. 马杜霉素铵对吸收过程几乎没有影响。

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