生长抑素和奥曲肽在急性胰腺炎治疗中的潜在作用。
Potential role of somatostatin and octreotide in the management of acute pancreatitis.
作者信息
Büchler M W, Binder M, Friess H, Malfertheiner P
机构信息
Department of Visceral and Transplantation Surgery, University of Bern, Switzerland.
出版信息
Digestion. 1994;55 Suppl 1:16-9. doi: 10.1159/000201183.
The pathophysiology of acute pancreatitis remains controversial. Activation of digestive enzymes in the pancreas may play an important role in the course of this disease. Therefore, the inhibition of enzyme secretion may be a possible treatment concept. However, it is not clear whether pancreatic secretion continues during the course of acute pancreatitis. In the present paper experimental and clinical studies are reviewed to evaluate the effect of somatostatin and octreotide treatment in acute pancreatitis.
急性胰腺炎的病理生理学仍存在争议。胰腺中消化酶的激活可能在该疾病的病程中起重要作用。因此，抑制酶分泌可能是一种可行的治疗理念。然而，目前尚不清楚在急性胰腺炎病程中胰腺分泌是否持续。本文对实验和临床研究进行综述，以评估生长抑素和奥曲肽治疗急性胰腺炎的效果。
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