Kneer I, Höh H, Ruprecht K W
Augenklinik und Poliklinik und Lehranstalt für Orthoptisten, Universität des Saarlandes.
Klin Monbl Augenheilkd. 1993 Dec;203(6):380-3. doi: 10.1055/s-2008-1045692.
Publications on the subject of conjunctiva in 1991 have been reviewed. Clinical relevant topics have been stressed. In the field of conjunctival affections caused by microorganisms a spectrum of bilateral squamous conjunctival tumors associated with human papillomavirus type 16 were first documented. Chlamydial antibodies cause proliferation of lymphocytes. The peripheral lymphocyte proliferative response to whole chlamydial elementary bodies seems to have a strong correlation between the responses to the Chlamydia trachomatis serotypes B and L1. In the field of impression cytology of the conjunctiva the topographical distribution of ocular surface cells was described. In patients with glaucoma using long-term topical medication, there seem to be significant degrees of conjunctival metaplasia associated with the number of glaucoma medications. These changes in the conjunctival surface may be related to the preservatives in the preparations (benzalkonium compounds). An ultrastructural defect in conjunctiva in recessive dystrophic epidermolysis bullosa may increase the susceptibility of the conjunctiva to minor mechanical trauma. Thus resulting in the bullous and cicatrical changes seen clinically.
对1991年有关结膜主题的出版物进行了综述。强调了临床相关主题。在由微生物引起的结膜疾病领域，首次记录了一系列与16型人乳头瘤病毒相关的双侧鳞状结膜肿瘤。衣原体抗体导致淋巴细胞增殖。对整个衣原体原体的外周淋巴细胞增殖反应似乎在对沙眼衣原体血清型B和L1的反应之间有很强的相关性。在结膜印片细胞学领域，描述了眼表细胞的地形分布。在长期使用局部药物的青光眼患者中，结膜化生程度似乎与青光眼药物的使用数量有关。结膜表面的这些变化可能与制剂中的防腐剂（苯扎氯铵化合物）有关。隐性营养不良性大疱性表皮松解症患者结膜的超微结构缺陷可能会增加结膜对轻微机械创伤的易感性。从而导致临床上出现大疱和瘢痕性变化。
