Raynauld J P, Bloch D A, Fries J F
Department of Medicine, Stanford University School of Medicine, CA.
J Rheumatol. 1993 Sep;20(9):1524-6.
The hypothesis of a seasonal pattern in the onset of symptoms for some vasculitides has been raised in previous small studies.
Using the data collected by the American College of Rheumatology (ACR) Subcommittee on Classification of Vasculitis, we specifically tested for a higher proportion of onset of symptoms in winter, lower in summer, and intermediate for the other seasons for polyarteritis nodosa (PAN) and Wegener's granulomatosis. We also tested for a higher proportion of onset of symptoms in the spring-summer months for giant cell arteritis (GCA).
The results of our study support the hypothesis of a seasonal trend for the onset of symptoms of Wegener's granulomatosis (p = 0.04) as described previously. No seasonal pattern was found for the other vasculitides studied (PAN and GCA).
先前的一些小型研究提出了某些血管炎症状发作存在季节性模式的假说。
利用美国风湿病学会（ACR）血管炎分类小组委员会收集的数据，我们专门针对结节性多动脉炎（PAN）和韦格纳肉芽肿病，测试冬季症状发作比例较高、夏季较低且其他季节居中的情况。我们还测试了巨细胞动脉炎（GCA）在春夏季症状发作比例较高的情况。
我们的研究结果支持先前所述的韦格纳肉芽肿病症状发作存在季节性趋势的假说（p = 0.04）。在所研究的其他血管炎（PAN和GCA）中未发现季节性模式。
