Small P M, Moss A
Department of Medicine, Stanford University, CA 94305.
Infect Agents Dis. 1993 Jun;2(3):132-8.
DNA fingerprinting techniques now exist which identify specific strains of Mycobacterium tuberculosis. These techniques may be integrated with conventional epidemiologic approaches to better understand tuberculosis in its modern form. This paper reviews the lessons learned from this approach about the pathogenesis and epidemiology of tuberculosis. In addition, it speculates about the potential future applications of molecular epidemiology, including its use as an adjunct to conventional public health measures.
现在已有DNA指纹识别技术可识别结核分枝杆菌的特定菌株。这些技术可与传统流行病学方法相结合，以便更好地了解现代形式的结核病。本文回顾了从这种方法中获得的有关结核病发病机制和流行病学的经验教训。此外，还推测了分子流行病学未来可能的应用，包括其作为传统公共卫生措施辅助手段的用途。
