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150例壶腹周围癌的临床分析

[Clinical analysis of 150 cases with periampullary carcinoma].

作者信息

Wu X D

机构信息

Fourth Affiliated Hospital of Hebei Medical College, Shijiazhuang.

出版信息

Zhonghua Zhong Liu Za Zhi. 1993 Jul;15(4):296-9.

PMID:7909747
Abstract

This article reported 150 cases of patients with periampullary carcinoma, among which cancer of 85 cases was in the head of pancreas, 26 in lower part of the common bile-duct, and 21 in ampulla of Vater and 18 in duodenal papilla. In 150 patients, pancreatoduodenectomy was performed in 53 cases but one had total pancreatectomy with a total resection rate of 36%. Resectability was high with cancer in ampulla and duodenal papilla, with a resection rate of 89.5% and 83.3%, respectively. The lowest resection rate, 14.1%, was in patients with cancer in head of the pancreas. Twenty cases had postoperative complications, the morbidity rate was 13.3%. Postoperative death occurred in 9 cases with a mortality rate of 6%. The resection group and non-resection group had 7.5 percent and 5.2 percent of the mortality respectively. Following-up showed that the 3 year and 5 year survival rates were 31.8% and 11.8% respectively. Fifty-four cases with resections had a mean survival period of 16.7 months. Ampullary carcinoma group had the longest survival period, 22.4 months, but non-resection group, all had bile-intestinal shunt, only 4.8 months.

摘要

本文报道了150例壶腹周围癌患者,其中85例癌位于胰头,26例位于胆总管下段,21例位于 Vater 壶腹,18例位于十二指肠乳头。150例患者中,53例行胰十二指肠切除术,但1例接受了全胰切除术,总切除率为36%。壶腹和十二指肠乳头癌的可切除性较高,切除率分别为89.5%和83.3%。胰头癌患者的切除率最低,为14.1%。20例发生术后并发症,发病率为13.3%。9例术后死亡,死亡率为6%。切除组和未切除组的死亡率分别为7.5%和5.2%。随访显示,3年和5年生存率分别为31.8%和11.8%。54例接受切除术的患者平均生存期为16.7个月。壶腹癌组生存期最长,为22.4个月,但未切除组均行胆肠吻合术,仅4.8个月。

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