Holinger P H, Kutnick S L, Schild J A, Holinger L D
Ann Otol Rhinol Laryngol. 1976 Sep-Oct;85(5 Pt.1):591-9. doi: 10.1177/000348947608500505.
Of 158 cases of subglottic stenosis 115 were congenital and 43 acquired. Current follow-up has been obtained in 146 (92%) which constitutes the determinate group. Although stridor was the most common presenting symptom of the congenital group, 34% presented with recurrent or prolonged episodes of croup. Tracheotomy was required in 47 of the 107 determinate cases (44%). Further management of the congenital cases was based on the experience that children outgrow this disorder; periodic dilatation may augment the natural process. Of those infants and children tracheotomized, all but five have been decannulated, and there was one death - a mortality rate of 2.1%. Acquired subglottic stenosis proved to be a more difficult management problem. Tracheotomy was necessary in 38 of the 39 determinate cases (97%). Repeated active dilatations for prolonged periods were usually required as well as endoscopic removal of granulation tissue. Of those infants and children tracheotomized, all but eight have been decannulated. There were nine deaths; five were due to unrelated underlying disease; four were attributable to complications of long-term tracheostomy. Thus, in the entire series, 85 infants and children required tracheotomy and five deaths may be attributable to long-term tracheostomy complications - a mortality rate of 5.9%.
在158例声门下狭窄病例中,115例为先天性,43例为后天性。已对146例(92%)进行了当前随访,这些病例构成了确定组。虽然喘鸣是先天性组最常见的首发症状,但34%的患儿表现为反复或迁延性喉炎发作。107例确定病例中有47例(44%)需要行气管切开术。先天性病例的进一步治疗基于儿童会逐渐摆脱这种疾病的经验;定期扩张可能会促进自然恢复过程。在接受气管切开术的婴幼儿中,除5例之外均已拔管,有1例死亡,死亡率为2.1%。后天性声门下狭窄被证明是一个更难处理的问题。39例确定病例中有38例(97%)需要行气管切开术。通常还需要长时间反复进行积极扩张以及内镜下清除肉芽组织。在接受气管切开术的婴幼儿中,除