School of Veterinary Science and Department of Epidemiology and Population Health, Institute of Infection and Global Health, School of Veterinary Science, Leahurst, University of Liverpool, Liverpool, UK.
28 Kings Road, Crosby, Merseyside, UK.
Epidemiol Infect. 2014 Jun;142(6):1196-204. doi: 10.1017/S0950268813002379. Epub 2013 Sep 25.
The faecal-pat prevalence (as estimated by culture) of Campylobacter fetus from cattle and sheep on 19 farms in rural Lancashire was investigated using standard Campylobacter culture techniques and PCR during a 2-year longitudinal study. C. fetus was isolated from 9·48% [95% confidence interval (CI) 8·48-10·48] of cattle faecal pats and 7·29% (95% CI 6·21-9·62) of sheep faecal pats. There was evidence of significant differences in shedding prevalence between geographical regions; cows in geographical zone 3 had an increased risk of shedding C. fetus compared to cows in geographical zones 1 and 2 (OR 6·64, 95% CI 1·67-26·5, P = 0·007), as did cows at pasture (OR 1·66, 95% CI 1·01-2·73, P = 0·046) compared to when housed. Multiple logistic regression modelling demonstrated underlying seasonal periodicity in both species.
在一项为期两年的纵向研究中，使用标准的弯曲杆菌培养技术和 PCR，调查了兰开夏郡农村 19 个农场的牛和羊粪便标本中胎儿弯曲杆菌的粪便阳性率（通过培养估计）。从 9.48%（95%置信区间为 8.48%至 10.48%）的牛粪便标本和 7.29%（95%置信区间为 6.21%至 9.62%）的绵羊粪便标本中分离出胎儿弯曲杆菌。在地理区域之间存在明显的粪便排出率差异的证据；与地理区域 1 和 2 的牛相比，地理区域 3 的牛排出胎儿弯曲杆菌的风险增加（OR 6.64，95%置信区间为 1.67-26.5，P = 0.007），而放牧的牛（OR 1.66，95%置信区间为 1.01-2.73，P = 0.046）与圈养的牛相比，排出风险也增加。多元逻辑回归模型显示，两种物种都存在潜在的季节性周期性。
