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[墨西哥尤卡坦州多次输血患者的I/II型人类嗜T细胞病毒感染]

[Infection by human T-cell lymphotropic virus type I/II in polytransfused patients in the state of Yucatán, Mexico].

作者信息

González-Martínez P, Castro-Sansores C, Vivas-Rosel M L, Góngora-Biachi R A

机构信息

Centro de Investigaciones Regionales, Dr. Hideyo Noguchi, Universidad Autónoma de Yucatán, México.

出版信息

Sangre (Barc). 1994 Feb;39(1):45-8.

PMID:7910984
Abstract

The relationship between several disorders, including adult T-cell leukaemia, and HTLV I/II virus infection has been clearly demonstrated. In order to assess the prevalence of such viral infection in a group of multiple-transfusion patients in the State of Yucatan, Mexico, a study was carried out on 140 patients with anti-HTLV-I/II antibodies demonstrated by ELISA and sensitized particles agglutination test. The patients had received 447 units of blood or blood components as a whole, and the mean time elapsed between the transfusion and the study was 2.5 years (range, 0.5-40), other risks of infection being discarded. No HTLV I/II reactivity was found along this study, thus showing the low prevalence and scarce risk for the transmission of this disease in Yucatan.

摘要

包括成人T细胞白血病在内的几种疾病与人类嗜T淋巴细胞病毒I/II(HTLV I/II)感染之间的关系已得到明确证实。为评估墨西哥尤卡坦州一组多次输血患者中此类病毒感染的流行情况,对140例经酶联免疫吸附测定(ELISA)和致敏颗粒凝集试验证实有抗HTLV-I/II抗体的患者进行了一项研究。这些患者总共接受了447单位的血液或血液成分,输血与研究之间的平均时间为2.5年(范围为0.5 - 40年),排除了其他感染风险。在这项研究中未发现HTLV I/II反应性,因此表明在尤卡坦州这种疾病的流行率较低且传播风险极小。

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