Madácsy L, Velösy B, Lonovics J, Csernay L
1st Department of Medicine, Albert Szent-Györgyi Medical University, Szeged, Hungary.
Eur J Nucl Med. 1994 Mar;21(3):203-8. doi: 10.1007/BF00188666.
Recurrent biliary pain after cholecystectomy is presumably due to sphincter of Oddi dysfunction (SOD). There is no ideal non-invasive test for SOD, and the diagnosis often relies on invasive procedures such as sphincter of Oddi (SO) manometry. Amyl nitrite-augmented quantitative hepatobiliary scintigraphy (QHBS) was performed on nine asymptomatic volunteers and 22 patients with SOD of biliary types I and II. Normal QHBS parameters were established in the asymptomatic volunteers. QHBS revealed a partial obstructive pattern in nine patients in whom SO stenosis was suspected and in 13 patients in whom SO dyskinesia was suspected. This obstructive pattern remained unchanged in the former group, but was completely relieved in the latter group of patients on amyl nitrite administration. In conclusion, amyl nitrite-augmented QHBS proved to be a useful non-invasive method in the diagnosis of SOD of biliary types I and II and permitted differentiation between organic stenosis and functional motor abnormalities of the SO.
胆囊切除术后复发性胆绞痛可能归因于Oddi括约肌功能障碍（SOD）。目前尚无理想的SOD非侵入性检测方法，诊断通常依赖于诸如Oddi括约肌（SO）测压等侵入性检查。对9名无症状志愿者以及22例I型和II型胆源性SOD患者进行了亚硝酸异戊酯增强定量肝胆闪烁显像（QHBS）检查。在无症状志愿者中确立了正常的QHBS参数。QHBS在9例怀疑有SO狭窄以及13例怀疑有SO运动障碍的患者中显示出部分梗阻模式。在前一组患者中这种梗阻模式保持不变，但在后一组患者中给予亚硝酸异戊酯后梗阻完全缓解。总之，亚硝酸异戊酯增强QHBS被证明是诊断I型和II型胆源性SOD的一种有用的非侵入性方法，并且能够区分SO的器质性狭窄和功能性运动异常。
