Hsiao Y L, Chang T C
Department of Internal Medicine, National Taiwan University Hospital, Taipei, R.O.C.
J Formos Med Assoc. 1994 Feb;93(2):140-4.
Typical examination of the thyroid gland involves palpating the patient. If goiter is found, thyroid ultrasonography and/or aspiration cytology is usually performed in addition to assay of thyroid hormones and antibodies. However, palpation may not be sensitive enough to detect thyroid lesions. The purpose of this study was to evaluate the prevalence of thyroid abnormalities detected by ultrasonography in Chinese adults without palpable thyroid glands admitted for health examination. Two hundred and seventy-seven patients (aged 17 to 79 years; mean, 52 years) admitted to National Taiwan University Hospital for health examinations were included in this study. The thyroid was first palpated by a thyroidologist. Goiter was detected in 77 out of 277 patients (27.8%). Two hundred patients who had no palpable goiter underwent thyroid ultrasonography. Thyroid abnormalities were detected in 37 out of 200 patients (18.5%). These included 18 cases of thyroid cyst, 13 cases of solid nodule, and six cases of multiple nodules with ill-defined margins. Patients with thyroid abnormalities were older than those without lesions [59.3 +/- 9.2 years (mean +/- SD) vs 50.1 +/- 12.8 years, p < 0.001]. In addition, we also calculated the thyroid volumes of 163 patients who had neither palpable goiter nor lesions detected by ultrasonography. The thyroid volumes were 7.7 +/- 3.3 mL and positively correlated to the body mass index (BMI, r = 0.17, p < 0.05) and body weight (r = 0.28, p < 0.005). Males (n = 115) had larger thyroid volume than females (n = 48) (8.3 +/- 3.3 vs 6.1 +/- 2.6 mL, p < 0.001).(ABSTRACT TRUNCATED AT 250 WORDS)
甲状腺的典型检查包括触诊患者。如果发现甲状腺肿大，除了检测甲状腺激素和抗体外，通常还会进行甲状腺超声检查和/或细针穿刺细胞学检查。然而，触诊检测甲状腺病变的灵敏度可能不够。本研究的目的是评估在中国因健康检查入院且甲状腺触诊无异常的成年人中，通过超声检查发现的甲状腺异常的患病率。本研究纳入了277名入住台湾大学附属医院进行健康检查的患者（年龄17至79岁，平均52岁）。首先由甲状腺专家进行甲状腺触诊。277名患者中有77名（27.8%）被检测出甲状腺肿大。200名未触及甲状腺肿大的患者接受了甲状腺超声检查。200名患者中有37名（18.5%）检测出甲状腺异常。其中包括18例甲状腺囊肿、13例实性结节和6例边界不清的多发结节。有甲状腺异常的患者比无病变的患者年龄更大[平均（59.3±9.2）岁 vs（50.1±12.8）岁，p<0.001]。此外，我们还计算了163名既未触及甲状腺肿大也未通过超声检测出病变的患者的甲状腺体积。甲状腺体积为（7.7±3.3）mL，与体重指数（BMI，r=0.17，p<0.05）和体重（r=0.28，p<0.005）呈正相关。男性（n=115）的甲状腺体积大于女性（n=48）（（8.3±3.3）mL vs（6.1±2.6）mL，p<0.001）。（摘要截断于250字）
