Saitoh Y, Kaneda K, Toyooka H, Amaha K
Department of Anaesthesiology and Critical Care Medicine, Faculty of Medicine, Tokyo Medical and Dental University, Japan.
Br J Anaesth. 1994 Jun;72(6):688-90. doi: 10.1093/bja/72.6.688.
We have studied post-tetanic count (PTC) and single twitch height at the onset of reflex movement to carinal stimulation after administration of vecuronium with five different types of anaesthesia. Seventy-five adult patients were allocated randomly to five groups of 15 patients each, to receive one of the following anaesthetics: neuroleptanaesthesia (fentanyl and droperidol) or 1 MAC of either halothane, isoflurane, enflurane or sevoflurane with 66% nitrous oxide in oxygen. During spontaneous recovery from vecuronium-induced neuromuscular block, the carina was stimulated with a suction catheter every 150 s. Single twitch heights at the onset of reflex movement were similar (2.0-2.7% of control values) between the five groups. In contrast, PTC at the onset of reflex movement to carinal stimulation differed (7.4-17.0) between groups.
我们研究了在使用五种不同类型麻醉剂给予维库溴铵后,对隆突刺激引发反射运动开始时的强直后计数(PTC)和单刺激颤搐高度。75名成年患者被随机分为五组,每组15名患者,分别接受以下麻醉剂之一:神经安定麻醉(芬太尼和氟哌利多)或1个最低肺泡有效浓度(MAC)的氟烷、异氟烷、恩氟烷或七氟烷,并在氧气中加入66%的氧化亚氮。在维库溴铵诱导的神经肌肉阻滞自然恢复过程中,每隔150秒用吸引导管刺激隆突。五组之间反射运动开始时的单刺激颤搐高度相似(为对照值的2.0 - 2.7%)。相比之下,对隆突刺激引发反射运动开始时的PTC在各组之间有所不同(7.4 - 17.0)。