Adler G, Markert U, Gattaz W F
Central Institute for Mental Health, Unit Neurobiology of Functional Psychoses, Mannheim, Germany.
Pharmacopsychiatry. 1994 Mar;27(2):68-9. doi: 10.1055/s-2007-1014280.
In a group of 33 acutely ill, previously unmedicated schizophrenic inpatients, the auditory-evoked potential components N1 and P2 were assessed and related to neuroleptic response measured as improvement of the BPRS score during a two-week neuroleptic treatment. N1 latency increase was found to be predictive for a poor neuroleptic response.
在一组33名急性发病、此前未接受过药物治疗的精神分裂症住院患者中,对听觉诱发电位成分N1和P2进行了评估,并将其与在为期两周的抗精神病药物治疗期间以简明精神病评定量表(BPRS)评分改善来衡量的抗精神病药物反应相关联。发现N1潜伏期延长可预测抗精神病药物反应不佳。