Keczkes K, Farr M
Br J Dermatol. 1976 Nov;95(5):541-6. doi: 10.1111/j.1365-2133.1976.tb00866.x.
Four of five patients with chronic renal failure developed tense bullae on the backs of their hands and fingers. In one of these patients the bullae were more widespread. In the fifth patient the lesions were limited to the fingers. The clinical picture resembled that of porphyria cutanea tarda, but porphyrin studies were consistently within normal limits. Histological studies showed subepidermal pressure bullae in each patient. In one of the patients immunohistology showed greenish fluorescence at the bases of the dermal papillae.
五名慢性肾衰竭患者中有四名在其手背和手指上出现了紧张性大疱。其中一名患者的大疱分布更为广泛。第五名患者的病变局限于手指。临床表现类似于迟发性皮肤卟啉症,但卟啉研究结果始终在正常范围内。组织学研究显示,每名患者均有表皮下压迫性大疱。其中一名患者的免疫组织学检查显示真皮乳头基部有绿色荧光。