柳氮磺胺吡啶诱发类风湿关节炎患者出现狼疮。
Sulfasalazine induced lupus in rheumatoid arthritis.
作者信息
Caulier M, Dromer C, Andrieu V, Le Guennec P, Fournie B
机构信息
Service de Rhumatologie, CHU Purpan, Toulouse, France.
出版信息
J Rheumatol. 1994 Apr;21(4):750-1.
PMID:7913504
Abstract
We describe 2 cases of a lupus syndrome induced by sulfasalazine in rheumatoid arthritis. All symptoms resolved and antihistone antibodies disappeared when sulfasalazine was discontinued. In one patient, perinuclear antineutrophil cytoplasmic antibodies with specificity for myeloperoxidase were found critically increased just before the occurrence of vasculitis.
摘要
我们描述了2例类风湿关节炎患者因柳氮磺胺吡啶诱发狼疮综合征的病例。停用柳氮磺胺吡啶后，所有症状均消失，抗组蛋白抗体也消失。在1例患者中，发现对髓过氧化物酶具有特异性的核周抗中性粒细胞胞浆抗体在血管炎发生前显著升高。
Zotero 插件