一名类风湿关节炎患者在接受柳氮磺胺吡啶治疗时出现药物性狼疮。
Drug-related lupus in a patient with rheumatoid arthritis under sulfasalazine treatment.
作者信息
Wildhagen K, Hartung K, Hammer M, Mau W, Schmidt R E, Deicher H, Zeidler H
机构信息
Abt. Immunologie, Medizinische Hochschule Hannover, Germany.
出版信息
Clin Rheumatol. 1993 Jun;12(2):265-7. doi: 10.1007/BF02231540.
PMID:8102951
Abstract
The induction of lupus-like syndromes with the appearance of single-stranded DNA antibodies is a well-known complication of drug therapy. In this report we present a patient with an erosive seropositive rheumatoid arthritis developing the clinical and serological features of systemic lupus erythematosus including the occurrence of double-stranded DNA antibodies under sulfasalazine treatment.
摘要
药物治疗引发狼疮样综合征并出现单链DNA抗体是一种众所周知的并发症。在本报告中，我们介绍了一名患有侵蚀性血清阳性类风湿性关节炎的患者，在柳氮磺胺吡啶治疗期间出现了系统性红斑狼疮的临床和血清学特征，包括双链DNA抗体的出现。
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