尼日利亚的真菌性角膜炎。21例病例研究。

Gugnani H C, Talwar R S, Njoku-Obi A N, Kodilinye H C

Br J Ophthalmol. 1976 Sep;60(9):607-13. doi: 10.1136/bjo.60.9.607.

A clinical and mycological study of 21 cases of mycotic keratitis, a clinical entity not yet reported from Nigeria or West Africa, showed that Fusarium solani was the predominant aetiological agent. It was isolated from 12 cases. Four of the remaining nine cases were caused by Aspergillus fumigatus, one by A. flavus, two by Penicillium citrinum, and one each by P. expansum and Penicillium sp. All the 12 isolates of F. solani grew well at 37 degrees C and survived at 40 degrees C. Two cases, one due to F. solani and the other to A. fumigatus, were accompanied by panophthalmitis.

对21例真菌性角膜炎患者进行的临床和真菌学研究表明，茄病镰刀菌是主要的病原体。尼日利亚或西非尚未报道过这种临床病症。在这21例患者中，从12例中分离出了茄病镰刀菌。其余9例中，4例由烟曲霉引起，1例由黄曲霉引起，2例由桔青霉引起，1例由扩展青霉引起，1例由青霉属引起。所有12株茄病镰刀菌在37摄氏度时生长良好，在40摄氏度时存活。2例患者，1例由茄病镰刀菌引起，另1例由烟曲霉引起，均伴有全眼球炎。