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尼日利亚的真菌性角膜炎。21例病例研究。

Mycotic keratitis in Nigeria. A study of 21 cases.

作者信息

Gugnani H C, Talwar R S, Njoku-Obi A N, Kodilinye H C

出版信息

Br J Ophthalmol. 1976 Sep;60(9):607-13. doi: 10.1136/bjo.60.9.607.

DOI:10.1136/bjo.60.9.607
PMID:791355
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1042779/
Abstract

A clinical and mycological study of 21 cases of mycotic keratitis, a clinical entity not yet reported from Nigeria or West Africa, showed that Fusarium solani was the predominant aetiological agent. It was isolated from 12 cases. Four of the remaining nine cases were caused by Aspergillus fumigatus, one by A. flavus, two by Penicillium citrinum, and one each by P. expansum and Penicillium sp. All the 12 isolates of F. solani grew well at 37 degrees C and survived at 40 degrees C. Two cases, one due to F. solani and the other to A. fumigatus, were accompanied by panophthalmitis.

摘要

对21例真菌性角膜炎患者进行的临床和真菌学研究表明，茄病镰刀菌是主要的病原体。尼日利亚或西非尚未报道过这种临床病症。在这21例患者中，从12例中分离出了茄病镰刀菌。其余9例中，4例由烟曲霉引起，1例由黄曲霉引起，2例由桔青霉引起，1例由扩展青霉引起，1例由青霉属引起。所有12株茄病镰刀菌在37摄氏度时生长良好，在40摄氏度时存活。2例患者，1例由茄病镰刀菌引起，另1例由烟曲霉引起，均伴有全眼球炎。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb7f/1042779/a19a5470f527/brjopthal00249-0008-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb7f/1042779/6e21c598c6d7/brjopthal00249-0004-a.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb7f/1042779/6ff598549afe/brjopthal00249-0006-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb7f/1042779/153370f287c0/brjopthal00249-0006-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb7f/1042779/1131d1f1c26b/brjopthal00249-0007-a.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb7f/1042779/35df8d47ea99/brjopthal00249-0008-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb7f/1042779/a19a5470f527/brjopthal00249-0008-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb7f/1042779/6e21c598c6d7/brjopthal00249-0004-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb7f/1042779/cdc92718a25a/brjopthal00249-0005-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb7f/1042779/6ff598549afe/brjopthal00249-0006-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb7f/1042779/153370f287c0/brjopthal00249-0006-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb7f/1042779/1131d1f1c26b/brjopthal00249-0007-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb7f/1042779/a05ad4fbb097/brjopthal00249-0007-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb7f/1042779/35df8d47ea99/brjopthal00249-0008-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb7f/1042779/a19a5470f527/brjopthal00249-0008-b.jpg

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本文引用的文献

1
Corneal and intra-ocular infection due to Fusarium solani.
Trans Ophthalmol Soc U K (1962). 1970;89:757-79.
2
Mycotic keratitis.
Indian J Ophthalmol. 1972 Sep;20(3):101-8.
3
Fusarium solani keratitis treated with natamycin (pimaricin): eighteen consecutive cases.用那他霉素（匹马霉素）治疗茄病镰刀菌角膜炎：连续18例。
Arch Ophthalmol. 1972 Aug;88(2):147-54. doi: 10.1001/archopht.1972.01000030149004.
4
J Fungi (Basel). 2018 Feb 8;4(1):23. doi: 10.3390/jof4010023.
4
Health Risks Associated with Exposure to Filamentous Fungi.与接触丝状真菌相关的健康风险。
Int J Environ Res Public Health. 2017 Jul 4;14(7):719. doi: 10.3390/ijerph14070719.
5
Penicillium keratitis in a HIV-infected patient.一名感染艾滋病毒患者的青霉性角膜炎
BMJ Case Rep. 2016 Aug 17;2016:bcr2016216139. doi: 10.1136/bcr-2016-216139.
6
Challenges of agriculture-related eye injuries in Nigeria.尼日利亚与农业相关的眼部损伤所面临的挑战。
Community Eye Health. 2015;28(91):52.
7
Murine model for Fusarium oxysporum invasive fusariosis reveals organ-specific structures for dissemination and long-term persistence.尖孢镰刀菌侵袭性镰刀菌病的小鼠模型揭示了传播和长期持续存在的器官特异性结构。
PLoS One. 2014 Feb 27;9(2):e89920. doi: 10.1371/journal.pone.0089920. eCollection 2014.
8
Diversity of microbial species implicated in keratitis: a review.与角膜炎相关的微生物物种多样性：综述
Open Ophthalmol J. 2012;6:110-24. doi: 10.2174/1874364101206010110. Epub 2012 Nov 30.
9
The etiology of infectious corneal ulceration in Sierra Leone.塞拉利昂感染性角膜溃疡的病因
Int Ophthalmol. 2010 Dec;30(6):637-40. doi: 10.1007/s10792-010-9348-1. Epub 2010 Jan 29.
10
Microbial keratitis in West Anatolia, Turkey: a retrospective review.土耳其安纳托利亚西部的微生物性角膜炎：一项回顾性研究。
Int Ophthalmol. 2007 Aug;27(4):261-8. doi: 10.1007/s10792-007-9069-2. Epub 2007 Apr 24.
Mycotic keratitis by Fusarium. A review and report of two cases.
镰刀菌性角膜炎。两例病例报告及文献综述
Ophthalmologica. 1975;170(1):1-12. doi: 10.1159/000307154.