• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

[Induction of autoantibodies to serotonin and catecholamines in chronically morphine addicted rats with manifestations of abstinence syndrome].

作者信息

Basharova L A, Evseev V A, Vetrilé L A, Trekova N A, Gamaleia N B, Veretinskaia A G, Tronnikov S I

出版信息

Biull Eksp Biol Med. 1993 May;115(5):469-71.

PMID:7913839
Abstract

The possibility of formation of autoantibodies to neurotransmitters has been studied in experimental model of opiate addiction. Chronic treatment of rats with morphine that leads to formation of dependence, causes induction of antibodies to norepinephrine, dopamine and serotonin. The latter could be considered as indicators of impaired neurotransmitter metabolism. Induction of autoantibodies to neurotransmitters could be a sort of defence mechanism in opiate addiction.

摘要

相似文献

1
[Induction of autoantibodies to serotonin and catecholamines in chronically morphine addicted rats with manifestations of abstinence syndrome].
Biull Eksp Biol Med. 1993 May;115(5):469-71.
2
[The effect of catecholamine and serotonin antibodies on pain sensitivity and the development of morphine tolerance in experimental drug addiction].[儿茶酚胺和血清素抗体对实验性药物成瘾中疼痛敏感性及吗啡耐受性形成的影响]
Biull Eksp Biol Med. 1993 Nov;116(11):453-5.
3
[Effect of active immunization with dopamine- and norepinephrine-protein conjugated on neurochemical and neurophysiologic parameters of withdrawal syndrome in chronically morphine-treated rats].
Patol Fiziol Eksp Ter. 1994 Apr-Jun(2):13-5.
4
[Antibody formation to morphine and neuromediators in morphinized rats].
Biull Eksp Biol Med. 1992 Dec;114(12):624-6.
5
Pharmacological analysis of certain mechanisms of morphine addiction.
Acta Physiol Pharmacol Bulg. 1976;2(2):68-74.
6
[Antibodies to neurotransmitters as possible neuroimmune risk markers of formation dependence to psychoactive substances].
Patol Fiziol Eksp Ter. 2013 Apr-Jun(2):13-6.
7
[Metabolic correction of neurochemical disturbances in the striatum by the amino-acid-based drug tavamin on the experimental model of morphine abstinence syndrome].
Eksp Klin Farmakol. 2009 Sep-Oct;72(5):15-7.
8
[A model of the depressive syndrome in rats induced by the neurotoxin MPTP and autoantibodies to serotonin and dopamine].
Zh Vyssh Nerv Deiat Im I P Pavlova. 1997 Jul-Aug;47(4):731-9.
9
[Antibodies to morphine and neuromediators in the blood serum of chronic alcoholics].
Biull Eksp Biol Med. 1987 Oct;104(10):460-2.
10
[Immunotherapy of experimental drug addiction with antibodies to serotonin and dopamine].
Biull Eksp Biol Med. 1996 Aug;122(8):189-92.

引用本文的文献

1
Immunization of rats with conjugates of dopamine and serotonin with bovine serum albumin prevents the development of experimental MPTP-induced depressive syndrome (electrophysiological parameters).
Neurosci Behav Physiol. 2004 Feb;34(2):131-8. doi: 10.1023/b:neab.0000009207.38914.2b.
2
Antibodies to dopamine as neuromodulators of behavioral responses of mice of different genotypes.
Neurosci Behav Physiol. 2003 Jun;33(5):507-12. doi: 10.1023/a:1023471402939.