Ulrich L
Institut für Rechtsmedizin, Bern.
Blutalkohol. 1994 May;31(3):165-77.
1,000 blood samples from drivers tested for alcohol were screened specifically for active constituents and metabolites of medicines of the benzodiazepine class. 42 blood samples contained benzodiazepines and a total of eight different active constituents were detected. The active constituents of Valium, Vegesan or Tranxilium, Lexotanil and Seresta have to be dealt with primarily. In addition to benzodiazepine 35 samples showed an alcohol level of over 0.08%. This raised the question of whether the benzodiazepine level measured in the blood samples would intensify the effect of the alcohol. Four categories were formed in order to be able to compare the levels of the various benzodiazepines. According to this categorisation the benzodiazepine concentration was classed as very high in 4 cases, high in 7 cases, moderate in 26 cases and low in 10 cases.
对1000份接受酒精检测的司机血液样本专门筛查了苯二氮䓬类药物的活性成分和代谢物。42份血液样本含有苯二氮䓬类药物，共检测出8种不同的活性成分。必须首先处理安定、维杰赞或氯氮䓬、利眠宁和司立吉林的活性成分。除苯二氮䓬类药物外，35份样本显示酒精含量超过0.08%。这就提出了一个问题，即血液样本中测得的苯二氮䓬类药物水平是否会增强酒精的作用。为了能够比较各种苯二氮䓬类药物的水平，划分了四类。根据这种分类，苯二氮䓬类药物浓度在4例中被归类为非常高，7例中为高，26例中为中等，10例中为低。
