Holmlund G, Wahlgren B, Lindblom B
State Institute of Forensic Serology, University Hospital, Linköping, Sweden.
Forensic Sci Int. 1994 Jun 3;66(2):105-9. doi: 10.1016/0379-0738(94)90334-4.
An allele with an internal HinfI restriction site has been found in the D12S11 locus. A three-fragment phenotype was revealed when the HinfI cleaved DNA was hybridised with the probe MS43A. Only two fragments were found when TaqI was used. These results have been confirmed with tests on a new sample drawn on a different occasion. This is the only three-band phenotype found out of 2800 unrelated individuals tested for this variable number of tandem repeats (VNTR) marker.
在D12S11基因座中发现了一个具有内部HinfI限制位点的等位基因。当用探针MS43A对经HinfI切割的DNA进行杂交时,显示出三片段表型。使用TaqI时仅发现两个片段。这些结果已通过对在不同时间采集的新样本进行测试得到证实。这是在对该可变串联重复序列(VNTR)标记进行测试的2800名无关个体中发现的唯一三带表型。