Rao C B, Rao D S, Satyanarayana C, Rao D V, Kassühlke K E, Faulkner D J
School of Chemistry, Andhra University, Visakhapatnam, India.
J Nat Prod. 1994 May;57(5):574-80. doi: 10.1021/np50107a002.
Five new cladiellane diterpenes, (1R*,2R*,3R*,6S*,7S*,9R*,10R*,14R*)-3- acetoxy-6-(3-methylbutanoyloxy)cladiell-11(17)-en-7-ol [2], (1R*,2R*,3R*,6S*,7S*,9R*, 10R*,14R*)-3-butanoyloxycladiell-11(17)-en-6,7-diol [3], (1R*,2R*,3R*,6S*,9R*,10R*,14R*)-3-acetoxycladiell-7(16),11(1 7)-dien-6-ol [4], 3-acetoxycladiell-11(17)-en-6-one [5], and its stereoisomer [6], have been isolated from the soft coral Cladiella australis collected on the coasts of the Andaman and Nicobar Islands of the Indian Ocean. In addition, sclerophytins C [7] and E [8], reported earlier from Sclerophytum capitalis, were also isolated. The structures of these metabolites were elucidated by interpretation of spectral data.
从印度洋安达曼和尼科巴群岛海岸采集的软珊瑚澳大利亚杯形珊瑚中分离出了五种新的克拉迪兰二萜，即(1R*,2R*,3R*,6S*,7S*,9R*,10R*,14R*)-3-乙酰氧基-6-(3-甲基丁酰氧基)克拉迪-11(17)-烯-7-醇[2]、(1R*,2R*,3R*,6S*,7S*,9R*,10R*,14R*)-3-丁酰氧基克拉迪-11(17)-烯-6,7-二醇[3]、(1R*,2R*,3R*,6S*,9R*,10R*,14R*)-3-乙酰氧基克拉迪-7(16),11(17)-二烯-6-醇[4]、3-乙酰氧基克拉迪-11(17)-烯-6-酮[5]及其立体异构体[6]。此外，还分离出了之前从首都硬叶藻中报道过的硬叶藻素C[7]和E[8]。这些代谢产物的结构通过光谱数据解析得以阐明。
