Lee S S, Li P C, Yeung K T, Sitt W H
Special Medical Consultation Clinic, Queen Elizabeth Hospital, Kowloon, Hong Kong.
Asian Pac J Allergy Immunol. 1993 Dec;11(2):131-3.
Seventeen asymptomatic HIV infected patients were studied for their phagocyte function in vitro, in comparison with that of eight normal healthy persons. Chemiluminescence was measured using whole blood by means of a microtitreplate luminometer. Light indices, cumulative light indices and rapidity of responses were recorded. The patients had a lower phagocyte count (13.17 +/- 0.85 x 10(9)/l) but a more rapid and intense chemiluminescence response. The latter was demonstrated by a higher peak light index and cumulative response. The observed enhanced phagocyte activity may reflect an early failure of T cell regulatory functions, or a compensatory mechanism in response to the underlying immunodeficiency.
对17例无症状HIV感染患者的体外吞噬细胞功能进行了研究，并与8名正常健康人的吞噬细胞功能进行了比较。采用微量滴定板发光计通过全血测量化学发光。记录了发光指数、累积发光指数和反应速度。患者的吞噬细胞计数较低（13.17±0.85×10⁹/L），但化学发光反应更快、更强烈。后者表现为更高的峰值发光指数和累积反应。观察到的吞噬细胞活性增强可能反映了T细胞调节功能的早期衰竭，或对潜在免疫缺陷的一种代偿机制。
