Cao W, Deng Y, Dong X, Wang Y, Lu Z
Institute of Acupuncture and Moxibustion, China Academy of Traditional Chinese Medicine, Beijing.
Zhen Ci Yan Jiu. 1993;18(1):48-52.
It has been demonstrated that electroacupuncture (EA) produces analgesia in acute arthritic animal models, while the differential analgesic effects at different EA parameters remains to be discovered. In the present experiment, the effects of EA at 100 Hz and 15 Hz on bilateral Yanglingpuan acupoints of the arthritic rats was studied. The results showed: 1) 15Hz EA was more effective than 10Hz EA for analgesia; 2) spinal glutamic acid content of the 15-Hz EA group was significantly lower than that of the 100-Hz EA group, and 3) no significant difference in GABA contents between the two groups was found. The results suggest that spinal glutamic acid may be involved in the different analgesic effects of EA at different frequencies in arthritic rats.
业已证明，电针在急性关节炎动物模型中可产生镇痛作用，而不同电针参数的差异镇痛效果仍有待发现。在本实验中，研究了100赫兹和15赫兹电针对关节炎大鼠双侧阳陵泉穴位的影响。结果显示：1）15赫兹电针的镇痛效果比100赫兹电针更有效；2）15赫兹电针组的脊髓谷氨酸含量显著低于100赫兹电针组；3）两组之间的GABA含量未发现显著差异。结果表明，脊髓谷氨酸可能参与了电针在关节炎大鼠中不同频率的差异镇痛作用。
