酒精摄入与血压：对日本自卫官的一项扩展研究。

Alcohol consumption and blood pressure: an extended study of self-defence officials in Japan.

作者信息

Wakabayashi K, Nakamura K, Kono S, Shinchi K, Imanishi K

机构信息

Department of Public Health, National Defense Medical College, Saitama, Japan.

出版信息

Int J Epidemiol. 1994 Apr;23(2):307-11. doi: 10.1093/ije/23.2.307.

DOI:10.1093/ije/23.2.307

PMID:7916005

Abstract

BACKGROUND

It remains controversial whether the relation between alcohol intake and blood pressure is linear or non-linear.

METHODS

The relation between alcohol intake and blood pressure was investigated in 2341 male self-defence officials who received a preretirement health examination at the Self-Defense Forces Fukuoka Hospital between October 1986 and December 1990. Average alcohol intake in the past year was ascertained by a self-administered questionnaire. The study excluded past drinkers, and allowed for smoking, body mass index and glucose tolerance.

RESULTS

Blood pressure was higher at higher levels of alcohol intake across the range from 0 to 40-59 ml of alcohol per day, but was not progressively higher in men consuming > or = 60 ml per day. Blood pressure was significantly higher even among light drinkers (< 20 ml per day) compared to non-drinkers; adjusted mean differences were 3.1 mmHg (95% confidence interval (CI): 1.1-5.2) in systolic pressure and 2.1 mmHg (95% CI: 0.7-3.5) in diastolic pressure.

CONCLUSIONS

Our findings do not support the existence of a threshold in the relation between alcohol and blood pressure.

摘要

背景

酒精摄入量与血压之间的关系是线性还是非线性仍存在争议。

方法

对1986年10月至1990年12月期间在自卫队福冈医院接受退休前健康检查的2341名男性自卫官员进行了酒精摄入量与血压关系的调查。过去一年的平均酒精摄入量通过自我管理问卷确定。该研究排除了既往饮酒者，并考虑了吸烟、体重指数和糖耐量。

结果

在每天酒精摄入量从0至40 - 59毫升的范围内，血压随酒精摄入量增加而升高，但每天饮酒量≥60毫升的男性血压并非持续升高。与不饮酒者相比，即使是轻度饮酒者（每天<20毫升）血压也显著更高；收缩压调整后平均差异为3.1 mmHg（95%置信区间（CI）：1.1 - 5.2），舒张压调整后平均差异为2.1 mmHg（95% CI：0.7 - 3.5）。