Department of Public Health, Kumamoto University School of Medicine, 2-2-1IIonjo, 860, Kumamoto, Japan.
Environ Health Prev Med. 1997 Jan;1(4):206-10. doi: 10.1007/BF02931218.
The estimation of risk for incidence of hypertension was carried out by follow-up study in a small village in Kumamoto Prefecture, Japan (N=750, 48.2±15.2months). The most significant risk in both sexes was blood pressure at entry. As for other risks, age, total cholesterol, and BMI in females were significant risks for systolic and diastolic blood pressure changes to greater than the borderline level. These factors in males were not significant. From the results of analysis using Cox's proportional hazards model, drinking in males was shown to be a significant risk for diastolic change, and in females for systolic change. It was concluded that excessive drinking in both sexes and obesity in females led to important health problems associated with hypertension among the subjects of the study.
在日本熊本县的一个小村庄进行的随访研究中,对高血压发病风险进行了评估(N=750,48.2±15.2 个月)。在男女两性中,最大的风险因素均为入组时的血压。对于其他风险因素,女性的年龄、总胆固醇和 BMI 是收缩压和舒张压变化超过临界水平的显著风险因素。而男性中这些因素并不显著。通过 Cox 比例风险模型分析的结果表明,男性饮酒是舒张压变化的显著风险因素,女性则是收缩压变化的显著风险因素。结论是,男女两性过度饮酒和女性肥胖会导致研究对象中与高血压相关的重要健康问题。