Mason G F, Pan J W, Ponder S L, Twieg D B, Pohost G M, Hetherington H P
Department of Medicine, University of Alabama at Birmingham 35294.
Magn Reson Med. 1994 Jul;32(1):142-5. doi: 10.1002/mrm.1910320121.
Brain glutamate and glutamine were detected in healthy human volunteers in spectroscopic images with a nominal voxel size of 2.25 cm3 at an echo time of 15 ms. Due to the increased frequency separation and simplification of J-coupling patterns, the separate detection of brain glutamate and glutamine at short echo times was possible. Creatine, choline, and N-acetylaspartate with other N-acetylated compounds were also detected. The ratios of the metabolite resonance intensities were in agreement with previously published values.
在回波时间为15毫秒、名义体素大小为2.25立方厘米的光谱图像中，对健康人类志愿者的大脑谷氨酸和谷氨酰胺进行了检测。由于频率分离增加以及J耦合模式简化，在短回波时间下能够分别检测大脑谷氨酸和谷氨酰胺。还检测到了肌酸、胆碱以及N - 乙酰天门冬氨酸与其他N - 乙酰化化合物。代谢物共振强度的比率与先前发表的值一致。
