Katenkamp D, Stiller D
Exp Pathol (Jena). 1976;12(3-4):203-13. doi: 10.1016/s0014-4908(76)80044-0.
Proliferating fibroblasts in subcutaneous connective tissue of rats after injection of peanut oil or implantation of an almost insoluble synthetic material (silicap) were characterized electron microscopically. In tissue samples of both the foreign body granulomas typical fibroblasts with abundant rough endoplasmic reticulum and a peculiar cellular modulation resembling histiocytes concerning their organelle composition were found. The morphological picture of the latter cells does not allow the conclusion that their function must be a merely phagocytic one. True myofibroblasts as detected in other stages of connective tissue proliferation are not present. The capillary vessels show a clear proliferation of their vascular cells and migration of these cells with assumption of fibroblastic features is suggested basing on morphological observations.
通过电子显微镜对注射花生油或植入几乎不溶性合成材料（硅胶）后大鼠皮下结缔组织中增殖的成纤维细胞进行了表征。在这两种异物肉芽肿的组织样本中，均发现了具有丰富粗面内质网的典型成纤维细胞，以及一种在细胞器组成方面类似于组织细胞的特殊细胞形态变化。后一种细胞的形态学特征并不能得出其功能仅仅是吞噬功能的结论。在结缔组织增殖的其他阶段检测到的真正肌成纤维细胞并不存在。毛细血管显示其血管细胞明显增殖，基于形态学观察推测这些细胞迁移并呈现出成纤维细胞特征。
